Introducing Inflection: Making What’s Next Matter
“I want to figure out what’s next.”
It’s something I hear often, at Zinc and beyond. And each time, it carries more than a question. It’s a signal of readiness. Not just for a job change, but for a shift in direction. A fresh alignment between skills and meaning. A willingness to step out of default and into design.
The people that ask me this are thoughtful, accomplished and hungry for more. They’ve built strong careers and skills. But they’re looking up and out, curious about how they can have more purpose, more impact, more meaning.
And there’s often a catalyst.
Sometimes it’s professional: it could be an exit, or a restructure, or a promotion that doesn’t feel quite right. Other times, it’s personal: the birth of a child, the experience of illness or bereavement, the emergence of a new perspective that makes old goals feel too small.
As I’ve written before, I’ve had those moments myself.
Whatever the cause, a quiet but urgent realisation takes root:
“It’s time to use your time and talent differently”
Of course, that’s easier said than done. When you’ve spent years climbing a ladder, it takes courage to ask whether it’s leaning against the right wall. And even more courage to consider what other walls (or ladders?) might exist.
I often think of what social theorist Pierre Bourdieu called social ageing – not the ageing of the body, but of the imagination. The way our sense of possibility narrows over time, shaped by identity, duty, and other people’s expectations.
We’re building a space to resist that contraction.
Having met over 15,000 people navigating career crossroads through our venture builder, coaching network and wider Zinc community, we saw a pattern: the desire for meaning and change, the weight of uncertainty, and – often – a quiet sense of isolation in this experience. We built Inflection to create a shared space for reflection, experimentation, and momentum.
It’s designed to help people reconnect with the ambition not just to succeed, but to matter. To shift from proving ourselves to improving ourselves – and, by doing so, the world around us..
A Changing World, A Call for New Problem-Solvers
This isn’t just a personal story. It’s a global one.
The future of work is no longer a distant horizon, it’s a shifting terrain we’re all navigating. As AI, climate change, demographic shifts, and political upheaval reshape every sector, the idea of a linear career path is fast becoming obsolete. As such, reinvention isn’t a luxury or a response to crisis, it’s a lifelong discipline. One that demands new tools, new communities, and new ways of thinking about what a career is for.
With this backdrop – and the profound shifts it reveals – we have the opportunity to reimagine how we allocate our talent differently
As the author David Brooks argues, the most underutilised resource in our society isn’t capital or time – it’s talent.
Indeed, we’re not suffering from a shortage of ideas, skills, or ambition, we’re suffering from a misdirection of them. Too much talent is stuck in the wrong problems: optimising ads, chasing margins, scaling what shouldn’t scale. And even those working on meaningful issues—researchers, scientists, clinicians—are too often trapped in broken systems, slow pathways, or institutional silos that blunt their potential.What we need now is a redirection – of energy, intelligence, and creativity – toward the challenges that define our time. Not just more talent, but talent aligned with purpose and in service of progress.
For us at Zinc, this redirection of talent is definitely more than personal. It’s core to our Science for Impact agenda. We believe some of the world’s most urgent problems – across health, the environment, education, and society – are not suffering from a shortage of knowledge, but from a shortage of people working on the right things or in the right way. Too often, scientific talent is underutilised, commercial talent is locked out of science, and innovation systems remain siloed and slow, not being able to fulfil the potential of the people who make those systems.
That’s why we built Inflection.
Inflection is the way we’re responding: helping talented people find their way into the problems that matter most, and creating new pathways that bring purpose and progress back into alignment.It sits at the intersection of two truths:
- People want more purposeful work.
- The world urgently needs better problem-solvers.
Bridging those truths takes work. It means asking harder questions about who work is for, and how we unlock talent where it’s most needed.
So What Gets in the Way?
The pace of technological and social change has made adaptability and self-authorship core career skills. But things get in the way:
- Internal blockers: fear of change, identity, belief and stagnation
- External ones: lack of visible entry points, sunk costs, permission structures, a lack of real models for nonlinear careers
We’ve learned that people don’t just need inspiration—they need the conditions to inflect:
- Catalyst – Create a moment and space to recalibrate what matters, where you can prototype and de-risk your future career.
- Coaching – Get clear about your north star and build awareness of your own patterns, mindset, and motivation
- Content – Find inspiration with tools, frameworks, and experiments to test what’s next
- Capital – Define your proposition, with access to people, ideas, science, and opportunities
- Community – Broaden your circle with a group that holds you to account and roots you in action and provides a positive social contagion for change.
We draw on what we’ve learned from years of venture building at Zinc, but we’ve adapted it for a different kind of challenge: personal transformation with mission impact. As the founder of LinkedIn Reid Hoffman says:
“All humans are entrepreneurs now.”
What You’ll Take Away
This isn’t a bootcamp. It’s not a sabbatical. It’s a space for building what’s next, with pace, depth, and support. Our methodology based on the conditions above, is rooted in five core principles:
→ Person-first
We start with a coaching mindset. Change begins with knowing yourself.
→ Mission and purpose driven
Human potential must serve missions, not just markets.
→ Action over introspection
We learn by doing. We test, build, iterate—with a bias toward action. As Herminia Ibarra reminds us:
“We learn who we are by acting, not by thinking.”
→ Interdisciplinarity
The future belongs to people with depth and range. Creative recombiners. Boundary-crossers.
→ Community as catalyst
You don’t do this alone. Talent unlocks impact. But community unlocks talent
We’re building a platform for career reinvention, not as a one-off intervention, but as an ongoing system of support, experimentation, and possibility, with new pathways, new tools, new offers, for individuals, teams, and organisations who are on and off, and between, the job.
In our pilot, 90%+ of participants reported increased clarity in their career direction, with participants taking concrete career actions during the 6-week programme. 100% of participants felt a shift from analysis paralysis to structured action, with new professional networks established with meaningful ongoing connections. Practical frameworks were adopted that participants continue to use independently, and there are striking mindset transformations – from rigid career thinking to adaptive, curious approaches.
What’s Next for You?
For me, building Inflection has been its own inflection point.
It’s brought together years of work on innovation, coaching, talent, impact and systems – and reminded me just how powerful it can be, at any stage of life, to ask with fresh eyes:
What’s next for me – and how can I make it matter?
And if that question is alive in you, we’d love to build with you.
Applications now open!
Applications are now open for the Inflection Explore Fellowship—a new opportunity to explore and experiment with what’s next, in your career and beyond, alongside a cohort of thoughtful, ambitious peers.
This is the first of several products and services we’re launching to help you design a life of greater impact and possibility.
👉 Places are limited and reviewed on a rolling basis – apply now to avoid missing out.
Join the Zinc community
Stay up to date with all Zinc updates and future posts as part of our fast growing community.
Featured Resources
Zinc Impact Report 2025
Science has the power to change the world – but only if the systems around it evolve. Zinc’s 2025 Science-for-Impact Report showcases a new model for how science, talent and capital can work together to tackle the most urgent challenges in health and the environment.
Across 38 pioneering Science-for-Impact ventures, a series of ecosystem-shaping partnerships and programmes, and a growing global community of talented innovators, the report demonstrates how frontier research is being transformed into scalable solutions for people and planet.
Through Zinc’s three pillars – Investment, Innovation Partnerships, and Inflection – Zinc is building the connective tissue of a new Science-for-Impact system. Explore the ventures, meet the founders, and see how you can join us in unlocking the extraordinary individuals who will unlock the future.
Zinc Impact Report 2024
Zinc’s mission is to make the UK the best place to successfully start a venture which can have a massive impact on the health of people and the planet.
Increasingly, we are building deeper science ventures that serve global, industrial customers in environment and health, giving access to impact at a global scale.
Our 2024 Impact Report explores the challenges that need to be tackled to empower and enable talented founders from around the world to solve critical health and environmental challenges at scale, from here in the UK.
This report showcases success stories from the Zinc portfolio, and highlights how Zinc – and our growing community of hundreds of Founders, Fellows, Coaches, Partners and Funders – are working together to build a world-leading “Science-for-Impact” ecosystem for inception stage ventures in health and environment.